America's Most Innovative Companies

What does innovation look like in 2025? From AI to autonomous vehicles, one company keeps setting the bar higher. This is the third year Fortune has published its list of America’s Most Innovative Companies in partnership with Statista, and for the third year in a row, Alphabet has come out on top.

The 300 companies on this year’s list brought in over $12.6 trillion in revenue for the latest 12 months, with the median revenue figure at $22 billion. The majority of companies on the 2025 list are based in California, in line with the previous years’ lists. And while the top three companies are all in the technology sector, health care made up a bigger portion of this year’s list than any other sector, with 63 companies represented.

America's Most Innovative Companies Ranking (2025)